Sheldon Saul Hendler See book keywords and concepts |
High doses of sodium fluoride (40-70 milligrams daily) used therapeutically even for long periods of time are unlikely to cause skeletal fluorosis. However, those who do take these doses may suffer from gastrointestinal symptoms, such as heartburn, and from pains in the feet and ankles. New forms of sodium fluoride are being developed to minimize the gastrointestinal symptoms.
2) Causes cancer—There is no evidence that fluoride ingestion causes any type of cancer.
IV. RECOMMENDATIONS
A) Suggested Intake: About 60 percent of the water supplies of the United States are fluoridated. |
Sheldon Saul Hendler and David Rorvik See book keywords and concepts |
A trend toward increased fluoride exposure has heightened concerns related to enamel and skeletal fluorosis, the incidences of which, however, still remain low.
RESEARCH SUMMARY
Sodium fluoride is approved by the Food and Drug Administration (FDA) for the prevention of dental caries. Fluoride is often added to public water supplies to achieve concentrations of 0.7 to 1.2 ppm. Higher concentrations (in the maximum 1.2 ppm range) are used in colder climates and lower concentrations in warmer climates where more water is typically consumed. |
| A specimen from the 78-year-old patient revealed osteomalacia and skeletal fluorosis. Researchers concluded that the fractures were caused by excessive fluoride retention due to renal insufficiency.
CONTRAINDICATIONS, PRECAUTIONS, ADVERSE REACTIONS
CONTRAINDICATIONS
Use of fluoride supplements is contraindicated in areas where fluoride water content is greater than 0.6 parts per million (ppm) or 0.6 milligrams per liter.
Fluoride supplements are contraindicated in those who are hypersensitive to any component of a fluoride-containing supplement. |
| Caries and fluorosis prevalence in communities with different concentrations of fluoride in the water. Caries Res. 1999; 33:114-122.
Dietary Reference Intakes for Calcium Phosphorus, Magnesium, Vitamin D, and Fluoride. Washington, DC: National Academy Press; 1997.
Guafiabens N, Farrerons J, Perez-Edo L, et al. Cyclical etidronate versus sodium fluoride in established postmenopausal osteoporosis: a randomized 3 year trial. Bone. 2000; 27:123-128.
Hillier S, Cooper C, Kelligray S, et al. Fluoride in drinking water and risk of hip fracture in the UK: a case-control study. Lancet. |
| Despite some reduction in exposure levels recommended by the American Academy of Pediatrics, incidence of dental fluorosis, while small, has continued to increase, a finding that some attribute to increased opportunities for fluoride exposure, not only from water but also from oral supplements, toothpastes, rinses, gels and some processed foods and beverages. Further modifications in recommended exposure levels are under consideration.
Because it is an effective osteoblast stimulator, fluoride has been investigated as a treatment for osteoporosis. |
| Dental fluorosis is characterized by mottled enamel.
INTERACTIONS
DRUGS
Aluminum hydroxide: Concomitant intake of aluminum hydroxide antacids and fluoride can cause decreased absorption of fluoride.
NUTRITIONAL SUPPLEMENTS
Calcium: Concomitant intake of a calcium supplement and fluoride can cause decreased absorption of fluoride.
FOODS
Concomitant intake of foods rich in calcium, such as milk or dairy products, can cause decreased absorption of fluoride. |
Thomas Bartram See book keywords and concepts |
Excess causes: fluorosis - mottling of teeth, arthritic joints and increased density of the bones. Controversial government policy promotes addition of Sodium flouride to water to achieve a minimum of one part per million.
FOLLICULITIS. Sycosis. Barber's itch. Inflammation of the hair follicles commencing as scattered pimples progressing to pustules on the scalp or beard.
Cause: mostly staphylococcal or streptococcal. Key agent: Thuja.
Alternatives. Blue Flag root, Burdock root.
Clivers, Garlic, Poke root. Red Clover flower,
Yellow Dock root. Echinacea root. |
James A. Howenstine, MD See book keywords and concepts |
Some children drinking fluoridated water develop an unsightly staining of their teeth called dental fluorosis, which leads to psychological problems in some of these children.
One of the unfortunate problems with fluoride is that it accumulates in the body, with the body having no good mechanism for removal.
Could The Daily Drinking Of Fluoride Be Contributing To The Rising Incidence Of Cancer In The United States?
A population study in the U.S.A. compared the 10 largest cities fluoridating their water with the 10 largest cities that did not fluoridate their water. |
Ruth Winter, M.S. See book keywords and concepts |
The trade association insisted that there is no current scientific evidence to indicate that fluorides in dentifrices can contribute to dental fluorosis. No known skin toxicity. See also Stannous Fluoride. SODIUM FORMATE • See Formic Acid
SODIUM GLUCONATE • Made from glucose by fermentation, a white to yellowish powder, it is used in metal cleaners, paint strippers, bottle-washing preparations, metal plating, and rust removers. Nontoxic.
SODIUM GLUTAMATE • The monosodium salt of the L-form of glutamic acid. See Glutamic Acid. |
Earl L. Mindell, R.Ph., Ph.D. See book keywords and concepts |
Some 30 percent of children in fluoridated communities have fluorosis, a malformation of tooth enamel that causes discoloration (usually chalky white patches) and brittleness. This is a permanent change in the teeth that has also been associated with abnormal bone structure.
Advocates of putting fluoride in toothpaste and mouthwash argue that it is not swallowed, and therefore not ingested. However, fluoride is absorbed through the mucous membranes of the mouth, and young children do not have control over their swallowing reflex. |
Ruth Winter See book keywords and concepts |
Chronic endemic fluorosis due to high concentration of natural fluoride in local water supplies involves mottling of the teeth, bone changes, and, rarely, brain and nerve involvement. Acute fluoride poisoning can cause heart, brain, nerve, and gastrointestinal damage. This is a substance for which a petition has been filed but the FDA has not allowed it a as a nutrient additive because "it has not been proven safe." SODIUM FORMATE • White, deliquescent crystals used in paper packaging. Moderately toxic by ingestion.
SODIUM GLUCONATE • Gluconic Acid. Sodium Salt. |
Textbook of Natural Medicine 2nd Edition Volume 2Michael T. Murray, ND See book keywords and concepts |
| Arthritis or skeletal fluorosis and boron. Int Clin Nutr Rev 1991; 11: 68-70
63. Wright V. Treatment of osteo-arthritis of the knees. Ann Rheum Dis 1964; 23: 389-391
64. Clarke GR, Willis LA, Stenner L, Nichols PJR. Evaluation of physiotherapy in the treatment of osteoarthrosis of the knee. Rheum Rehab 1974; 13: 190-197
65. Vanharantha H. Effect of short-wave diathermy on mobility and radiological stage of the knee in the development of experimental osteoarthritis. Am J Phys Med 1982; 61: 59-65
66. Falconer J, Hayes KW, Chang RW. |
Nicola Reavley See book keywords and concepts |
Children living in areas were the water is fluoridated are at increased risk of dental fluorosis, in which teeth become mottled with yellow or brown spots. Bottle fed babies are at particular risk if formula is made with fluoridated tap water. Breast milk and ready-to-feed formula contain safe fluoride levels and experts recommend using low fluoride filtered or distilled water with formula. Fluoridation may also increase the risk of dermatitis in sensitive people.
Tooth decay
Fluoride is used in the treatment of dental caries. |
| A study published in 1997 in the Journal of the American Dental Association suggest that some commercially available infant foods contain high levels of fluoride which may put babies at risk of fluorosis. Some foods, particularly those containing chicken, are processed in ways which lead to high fluoride concentrations. Adding water to dry baby food also increases fluoride content.2
Therapeutic uses of supplements
Fluoridation of water
Approximately half of the US water supply is fluoridated in an effort to reduce tooth decay. |
| If large quantities (20 to 80 mg per day) are taken for long periods skeletal fluorosis may occur. Appetite is depressed, the joints become stiff and painful, the spine, pelvis and limb bones become denser and calcium can be deposited in the muscles and tendons. Fatal poisoning can occur if fluoride is taken in amounts greater than 2500 times the recommended dose.
There is some evidence linking fluoride in water to various types of cancer, although many studies have not found any connection. |
| The amount necessary to protect against tooth decay without causing fluorosis is used as a basis for calculating these values.
Men Women Children Children
6 to 12 months 4 to 8 years
Children 9 to 13
USA 3.8 mg 3.1 mg 0.5 mg 1.1 mg
2.0 mg
The daily tolerable upper intake levels for fluoride are:
Men Women Children Children
6 to 12 months 4 to 8 years
Children 9 to 18
USA 10 mg 10 mg 0.9 mg 2.2 mg
10 mg
In most developed countries, fluoride is added to drinking water at a concentration of one part per million. This supplies between 1 and 2 mg fluoride per day. |
Linda Mason Hunter See book keywords and concepts |
Long-term chronic ingestion at higher levels can lead to skeletal fluorosis, which has symptoms resembling those of arthritis, and may produce mottling of teeth, especially in children.
MUNICIPAL WASTE TREATMENT PLANTS The EPA found in 1988 that three out of every four municipal waste treatment plants have not kept industrial toxic chemicals from polluting tap water. Between 100,000 and 200,000 industries of varying size pump their wastes directly into sewers, where it mingles with the wastes of millions of households and other nontoxic sources. |
Michael F. Jacobson, Ph.D., Lisa Y. Lefferts and Anne Witte Garland See book keywords and concepts |
| According to the EPA, assuming average dietary levels of fluoride, up to 1 ppm in water won't cause dental fluorosis.
Be sure your children are getting enough fluoride, but not too much. Find out how much fluoride is in your tap water (see page 132) or bottled water (ask the manufacturer). Teach your children to rinse thoroughly after brushing their teeth, and not to swallow toothpaste. And urge the EPA to lower the current legal limit of 4 ppm fluoride in drinking water to no greater than 1 ppm. problem in houses or buildings that are either very old or very new. |
Gary Null See book keywords and concepts |
Fluoride is carcinogenic, and an immune suppressant that causes dental fluorosis (white or brown spots on the teeth). It increases the tendency to hip fracture by poisoning the bones.
HISTORICAL PERSPECTIVE Why did this dangerous substance, with no real protective qualities, become so widely adopted? In the 1940s there was a crisis in the aluminum industry, with big companies such as Alcoa being sued for polluting and killing cattle and other livestock. |
Schuyler W. Lininger, Jr. DC See book keywords and concepts |
Arthritis or skeletal fluorosis and boron. Int Clin Nutr Rev 1991; 11: 68-70 [letter].
45. Balagot RC, Ehrenpreis S, Kubota K, et al. Analgesia in mice and humans by D-phenylalanine: Relation to inhibition of enkephalin degradation and enkephalin levels. Adv Pain Res Ther 1983; 5: 289-93.
46. American Medical Association. Dimethyl sulfoxide. Controversy and Current Status— 1981. JAMA 1982; 248: 1369-71.
47. Jimenez RAH, Willkens RF. Dimethyl sulfoxide: A perspective of its use in rheumatic diseases. / Lab Clin Med 1982; 100: 489-500.
48. Jacob SW, Wood DC. Dimethyl sulfoxide (DMSO). |
Dr Bernard Jenson and Mark Anderson See book keywords and concepts |
Early stages of skeletal fluorosis: "Doses as low as 2 to 5 milligrams per day [the amount of two to five liters of one ppm of fluoridated water] can cause the preclinical and early clinical stages." (Page 35.) This is generally unrecognized in the United States because "Most doctors in the U.S. ... do not know how to diagnose it." (Page 37.)
Osteoporosis and fluoride treatment: "Well-designed studies have found no evidence of a beneficial effect [of fluoridation] on osteoporosis." (Page 39. |
| Page 33.)
Early stages of skeletal fluorosis: "Doses as low as 2 to 5 milligrams per day [the amount of two to five liters of one ppm of fluoridated water] can cause the preclinical and early clinical stages." (Page 35.) This is generally unrecognized in the United States because "Most doctors in the U.S. ... do not know how to diagnose it." (Page 37.)
Osteoporosis and fluoride treatment: "Well-designed studies have found no evidence of a beneficial effect [of fluoridation] on osteoporosis." (Page 39. |
Sheldon Saul Hendler and David Rorvik See book keywords and concepts |
Observational studies at the time led to the conclusion that those who lived in areas with a high incidence of dental fluorosis also had a lower incidence of caries than those who lived in areas where the fluoride intake was low.
In 1945, water fluoridation began in Grand Rapids, Michigan as a public health measure to reduce the incidence of caries. Presently, approximately 60% of community water supplies in the United States contain fluoride from 0.7 to 1.2 parts per million or 0.7 to 1.2 milligrams per liter.
Fluoride is the anionic form of fluorine. |
Gary Null, Ph.D. See book keywords and concepts |
Reversal of Clinical and Dental fluorosis," Indian Pediatr, 31(4),
April 1994, p. 439-443.
General
This review article notes that while excessive intracellular calcium accumulation can results in cell damage; high calcium intake may be effective in the treatment of such unrelated diseases as arterial hypertension, nephrolithiasis, colon cancer, etc.
—G. Palmieri, "New Perspectives in Calcium Metabolism," Medicina B. Aries, 53(5), 1993, p. 459-466.
Hip Fracture
Results of this 3-year study found that supplementation with 1. |
Textbook of Natural Medicine 2nd Edition Volume 1Michael T. Murray, ND See book keywords and concepts |
| Action of boron upon fluorosis and calcium-phosphorous metabolism: an experimental study. Fluoride 1982; 15: 75-78
27. Pinto J, Huang YP, McConnell RI et al. Increased urinary riboflavin excretion resulting from boric acid ingestion. J Lab Clin Med 1978; 92: 126-134
28. Gilbert FA. Mineral nutrition of plants and animals. Norman: Univ OK Press. 1984: p 80-84
29. Travers RL, Rennie GC, Newnham RE. Boron and arthritis: the results of a double-blind pilot study. J Nutr Med 1990; 1: 127-132
30. Nielsen FH. |
Dr. John Yiamouyiannis See book keywords and concepts |
Chapter 6).
4) Only one laboratory found that fluoride caused genetic damage—when in fact over ten laboratories did (see Chapter 8).
5) They could find "no data concerning mutagenic effect of fluoride on humans"—when in fact there are (see Chapter 8).
6) They could find "no information on the teratogenicity of fluoride"—when in fact there is (see Chapter 8).
7) They could find no information on the carcinogenicity of fluoride—when in fact there is (see Chapter 8). |